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Summary: Clinical Pharmacology Insights into Patient Care
Panel Discussion Overview: Moderated by Dr. Shambo Samrat Samajdar with insights from Prof. Jyotirmoy Pal, Prof. Santanu K Tripathi, Prof. Nandini Chatterjee, and Prof. Sandhiya Selvarajan, this session explored practical applications of clinical pharmacology principles in patient care.
Key Topics:
1. Polypharmacy:
High prevalence globally and in India among the elderly, often associated with increased risk of adverse outcomes.
Challenges include inappropriate medication use, undertreatment, and anticholinergic burden.
Strategies like clinical pharmacological reconciliation and review ensure safe prescribing.
2. Prescribing Cascade:
Avoid initiating medications to treat side effects of others unnecessarily.
Deprescribing emphasized as a systematic and patient-centered approach.
3. Dose Modifications:
Critical for patients with chronic kidney disease (CKD) or chronic liver disease (CLD).
Factors like hepatic extraction ratio, intrinsic clearance, and altered pharmacokinetics guide adjustments.
4. Drug-Induced Disorders:
Examples included interactions between linezolid and digoxin, highlighting the importance of therapeutic drug monitoring (TDM).
Managing adverse effects and ensuring optimal drug levels were stressed.
5. Case Studies:
Detailed cases illustrated challenges of polypharmacy, prescribing cascades, and dose adjustments in vulnerable patients.
Take-Home Messages:
Rationalize polypharmacy.
Prevent prescribing cascades.
Tailor dose modifications for CKD/CLD patients.
View deprescribing as a positive, collaborative intervention.
Focus on a patient-centric approach for safe and effective clinical pharmacological care.
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The Role of Accountability Partners in Kelly Clarkson Weight Loss Journey
Kelly Clarkson's weight loss journey is a testament to her determination and commitment to achieving optimal health. While many aspects contribute to her success, one crucial factor that played a significant role in her transformation was having accountability partners.
Having the Right Support System: A Key Factor in Successful Weight Loss
In an interview with People Magazine, Clarkson revealed that she credits part of her weight loss journey to having friends who kept her on track. Having people around you who understand and support your goals is essential for maintaining motivation during challenging times. When Kelly's husband proposed the idea of starting a new exercise routine together, it not only made working out more enjoyable but also gave them both an added level of accountability.
Dietary Changes That Fostered Sustainable Weight Loss
Clarkson has discussed her dietary changes extensively throughout her weight loss journey. One key component was incorporating keto-based meals into her daily intake to boost fat burning and manage hunger efficiently. By adopting these sustainable eating habits, she not only saw improvements in overall health but also discovered a healthier relationship with food.
Importance of Mindful Eating for Sustainable Weight Loss
Maintaining mindfulness while consuming is vital during weight loss endeavors. Clarkson emphasized the importance of listening to her body's cues about satiety and taking necessary breaks when required. By adopting mindful eating practices, individuals can better understand their bodies' needs and make more informed choices that support long-term health goals.
Why Tracking Progress Matters in Weight Loss Journeys
Monitoring progress is another crucial element for successful weight loss journeys. Clarkson keeps track of her daily milestones using a fitness app to stay on course with set objectives and see the positive changes happening over time, regardless of whether it's an increase in exercise or reduction in calories consumed.
Physical Exercise: An Essential Component of Kelly Clarkson's Weight Loss Journey
Regular physical activity is another significant component that contributed significantly to Kelly Clarkson's weight loss journey. Regular cardio sessions complemented with strength training exercises help maintain muscle mass while burning excess fat, leading towards more desirable body composition and increased metabolism for long-term success.
Celebrating Small Victories: A Powerful Tool in Maintaining Motivation
Celebrating small victories along the way can significantly contribute to maintaining motivation throughout weight loss journeys. When Kelly hit specific milestones during her journey, whether it was losing a certain amount of weight or fitting into smaller sizes, she allowed herself time and effort to celebrate these achievements through activities that bring joy.
The Significance of Staying Hydrated During Weight Loss
Hydration plays an essential role in overall health but also affects the progress seen throughout weight loss endeavors. Drinking plenty of water can increase metabolism rates while assisting the body's capacity to shed unwanted fat more efficiently, thereby fostering quicker results and enhanced energy levels necessary for achieving set objectives.
By incorporating these strategies into one's own weight loss journey, they'll likely encounter fewer obstacles along the way as well as a higher probability of maintaining long-term success.
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